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Proteomic Characterization of Early Changes Induced by Triiodothyronine in Rat Liver
Journal of Proteome Research · 2011
DOI: 10.1021/pr200244fEffect of thyroid hormones on acid cholesterol ester hydrolase activity in rat liver, heart and epididymal fat pads
Biochimica et Biophysica Acta (BBA) - General Subjects · 1981
DOI: 10.1016/0304-4165(81)90235-xEffects of Thyroid Status on the Structure of the Very Low Density Lipoprotein Secreted by the Perfused Liver*
Endocrinology · 1982
DOI: 10.1210/endo-110-2-551Hepatic organic anion transporting polypeptide transporter and thyroid hormone receptor interplay determines cholesterol and glucose homeostasis
Hepatology · 2011
DOI: 10.1002/hep.24391Impaired Revascularization in a Mouse Model of Type 2 Diabetes Is Associated With Dysregulation of a Complex Angiogenic-Regulatory Network
Arteriosclerosis, Thrombosis, and Vascular Biology · 2005
DOI: 10.1161/01.atv.0000171994.89106.caEndothelial PGC-1α Mediates Vascular Dysfunction in Diabetes
Cell Metabolism · 2014
DOI: 10.1016/j.cmet.2013.12.014Adenoviral transfer of HIF-1α enhances vascular responses to critical limb ischemia in diabetic mice
Proceedings of the National Academy of Sciences · 2009
DOI: 10.1073/pnas.0910561106Induction of Angiogenesis by a Type III Phosphodiesterase Inhibitor, Cilostazol, Through Activation of Peroxisome Proliferator-Activated Receptor-γ and cAMP Pathways in Vascular Cells
Arteriosclerosis, Thrombosis, and Vascular Biology · 2016
DOI: 10.1161/atvbaha.115.307011Levothyroxine Replacement in Hypothyroid Humans Reduces Myocardial Lipid Load and Improves Cardiac Function
The Journal of Clinical Endocrinology & Metabolism · 2014
DOI: 10.1210/jc.2014-2112Effects of hypothyroidism and high-fat feeding on mRNA concentrations for the low-density-lipoprotein receptor and on acyl-CoA:cholesterol acyltransferase activities in rat liver
Biochemical Journal · 1991
DOI: 10.1042/bj2760825Safety and efficacy of resmetirom in metabolic dysfunction-associated steatohepatitis (MASH): a systematic review and meta-analysis
European Journal of Gastroenterology & Hepatology · 2025
DOI: 10.1097/meg.0000000000002901Resmetirom: The First FDA-Approved Drug for Metabolic Dysfunction-Associated Steatohepatitis (MASH) with a Perspective on Precision Medicine
Clinical Drug Investigation · 2025
DOI: 10.1007/s40261-025-01484-1Safety and efficacy of resmetirom in the treatment of patients with non-alcoholic steatohepatitis and liver fibrosis: a systematic review and meta-analysis
Annals of Medicine & Surgery · 2024
DOI: 10.1097/ms9.0000000000002195Relationship between impaired sensitivity to thyroid hormones and MAFLD with elevated liver enzymes in the euthyroid population
International Journal of Diabetes in Developing Countries · 2024
DOI: 10.1007/s13410-023-01308-yModulation by Thyroid Status of the Actions of Glucagon and Dibutyryl Adenosine 3',5'-Monophosphate on Metabolism of Free Fatty Acids by the Isolated Perfused Rat Liver*
Endocrinology · 1982
DOI: 10.1210/endo-110-5-1740Experimental hypothyroidism modulates the expression of the low density lipoprotein receptor by the liver
Atherosclerosis · 1986
DOI: 10.1016/0021-9150(86)90129-2Hypothyroidism/subclinical hypothyroidism and metabolic dysfunction-associated steatotic liver disease: advances in mechanism and treatment
Lipids in Health and Disease · 2025
DOI: 10.1186/s12944-025-02474-0The correlation between triiodothyronine and the severity of liver fibrosis
BMC Endocrine Disorders · 2022
DOI: 10.1186/s12902-022-01228-8Translational development of ABCB5+ dermal mesenchymal stem cells for therapeutic induction of angiogenesis in non-healing diabetic foot ulcers
Stem Cell Research & Therapy · 2022
DOI: 10.1186/s13287-022-03156-9Low thyroid function is associated with an increased risk of advanced fibrosis in patients with metabolic dysfunction-associated fatty liver disease
BMC Gastroenterology · 2023
DOI: 10.1186/s12876-022-02612-3Resmetirom, the first FDA-approved drug for MASH: From drug discovery and action mechanisms to clinical trials
Archives of Pharmacal Research · 2025
DOI: 10.1007/s12272-025-01574-wResmetirom in the Management of MASLD: What Clinicians Need to Know
Current Hepatology Reports · 2025
DOI: 10.1007/s11901-025-00708-4Resmetirom for Steatotic Liver Disease: Does Data Support Widespread Use?
Current Gastroenterology Reports · 2025
DOI: 10.1007/s11894-025-01002-5S2828 Targeting THR-β in Nonalcoholic Steatohepatitis (NASH): A Meta-Analysis of Resmetirom's Efficacy and Safety
American Journal of Gastroenterology · 2025
DOI: 10.14309/01.ajg.0001138772.41014.6dPGC-1α Induces SPP1 to Activate Macrophages and Orchestrate Functional Angiogenesis in Skeletal Muscle
Circulation Research · 2014
DOI: 10.1161/circresaha.115.303829Efficacy of tirzepatide, lanifibranor, and resmetirom in metabolic dysfunction-associated steatotic liver disease: a meta-analysis of high-quality randomized controlled trials
Internal and Emergency Medicine · 2026
DOI: 10.1007/s11739-026-04326-wPassive Exercise Using Whole-Body Periodic Acceleration Enhances Blood Supply to Ischemic Hindlimb
Arteriosclerosis, Thrombosis, and Vascular Biology · 2011
DOI: 10.1161/atvbaha.111.229773Why is coronary collateral growth impaired in type II diabetes and the metabolic syndrome?
Vascular Pharmacology · 2012
DOI: 10.1016/j.vph.2012.02.001Angiographic Demonstration of Neoangiogenesis after Intra-arterial Infusion of Autologous Bone Marrow Mononuclear Cells in Diabetic Patients with Critical Limb Ischemia
Cell Transplantation · 2011
DOI: 10.3727/096368910x0177Ablation of angiotensin type 2 receptor prevents endothelial nitric oxide synthase glutathionylation and nitration in ischaemic abductor muscle of diabetic mice
Diabetes and Vascular Disease Research · 2020
DOI: 10.1177/1479164119883978Rescue of Diabetes-Related Impairment of Angiogenesis by Intramuscular Gene Therapy with Adeno-VEGF
The American Journal of Pathology · 1999
DOI: 10.1016/s0002-9440(10)65282-0Thyroid Hormone Signaling and the Liver
Hepatology · 2020
DOI: 10.1002/hep.31296Gene therapy for therapeutic angiogenesis in critically ischaemic lower limb – on the way to the clinic
European Journal of Clinical Investigation · 2001
DOI: 10.1046/j.1365-2362.2001.00864.xResmetirom. Thyroid hormone receptor-beta agonist, Treatment of nonalcoholic steatohepatitis
Drugs of the Future · 2020
DOI: 10.1358/dof.2020.45.12.3191006Autologous Cell Therapy for Peripheral Arterial Disease: Systematic Review and Meta-Analysis of Randomized, Nonrandomized, and Noncontrolled Studies
Circulation Research · 2017
DOI: 10.1161/circresaha.116.309045Metabolic reprogramming by HIF-1 promotes the survival of bone marrow–derived angiogenic cells in ischemic tissue
Blood · 2011
DOI: 10.1182/blood-2010-11-321190Resmetirom and Metabolic Dysfunction-Associated Steatohepatitis: Perspectives on Multidisciplinary Management from Global Healthcare Professionals
Current Obesity Reports · 2024
DOI: 10.1007/s13679-024-00582-zPlatelet-derived growth factor C promotes revascularization in ischemic limbs of diabetic mice
Journal of Vascular Surgery · 2014
DOI: 10.1016/j.jvs.2013.04.053Human diabetic mesenchymal stem cells from peripheral arterial disease patients promote angiogenesis through unique secretome signatures
Surgery · 2018
DOI: 10.1016/j.surg.2017.11.018Thyroid Hormone Regulates Hepatic Triglyceride Mobilization and Apolipoprotein B Messenger Ribonucleic Acid Editing in a Murine Model of Congenital Hypothyroidism
Endocrinology · 2003
DOI: 10.1210/en.2002-220741Repurposing Resmetirom suppresses MASH-associated hepatocellular carcinoma, with mechanistic implications of MDK/LRP1-mediated metabolic reprogramming and immunosuppression
Hepatology · 2026
DOI: 10.1097/hep.0000000000001675Regional angiogenesis with vascular endothelial growth factor (VEGF) in peripheral arterial disease: Design of the RAVE trial
American Heart Journal · 2003
DOI: 10.1016/s0002-8703(03)00102-9Regional Angiogenesis With Vascular Endothelial Growth Factor in Peripheral Arterial Disease: A Phase II Randomized, Double-Blind, Controlled Study of Adenoviral Delivery of Vascular Endothelial Growth Factor 121 in Patients With Disabling Intermittent Claudication
Circulation · 2003
DOI: 10.1161/01.cir.0000093398.16124.29Effect of dietary composition on liver glycogen accumulation and lipid metabolism in the hypothyroid chick (Gallus domesticus)
Comparative Biochemistry and Physiology Part A: Physiology · 1978
DOI: 10.1016/0300-9629(78)90272-4Concise Review: Cell Therapy for Critical Limb Ischemia: An Integrated Review of Preclinical and Clinical Studies
Stem Cells · 2018
DOI: 10.1002/stem.2751Angiogenic gene therapy does not cause retinal pathology
The Journal of Gene Medicine · 2014
DOI: 10.1002/jgm.2806Thyroid dysfunction in MASLD: Results of a nationwide study
JHEP Reports · 2025
DOI: 10.1016/j.jhepr.2025.101369Response to T3treatment and changing environmental salinity of liver lipid composition, mitochondrial respiration and (Na++ ++ K++)-ATPase activity in rainbow troutOncorhynchus mykissWalbaum: Trout liver response to T3and salinity
Aquaculture Research · 2002
DOI: 10.1046/j.1365-2109.2002.00729.xA novel potential therapy for vascular diseases: blood-derived stem/progenitor cells specifically activated by dendritic cells
Diabetes/Metabolism Research and Reviews · 2014
DOI: 10.1002/dmrr.2543Lack of thyroid hormone receptor beta is not detrimental for non-alcoholic steatohepatitis progression
iScience · 2023
DOI: 10.1016/j.isci.2023.108064Type 2 cytokines promote angiogenesis in ischemic muscle via endothelial IL-4Rα signaling
Cell Reports · 2023
DOI: 10.1016/j.celrep.2023.112964Adipose-derived stem cell-secreted exosomes enhance angiogenesis by promoting macrophage M2 polarization in type 2 diabetic mice with limb ischemia via the JAK/STAT6 pathway
Heliyon · 2022
DOI: 10.1016/j.heliyon.2022.e11495Allogenic Vertebral Body Adherent Mesenchymal Stromal Cells Promote Muscle Recovery in Diabetic Mouse Model of Limb Ischemia
Annals of Vascular Surgery · 2025
DOI: 10.1016/j.avsg.2024.08.004Resmetirom for treatment of MASH
Cell · 2024
DOI: 10.1016/j.cell.2024.05.009Thyroid hormone receptor-beta agonist HSK31679 alleviates MASLD by modulating gut microbial sphingolipids
Journal of Hepatology · 2025
DOI: 10.1016/j.jhep.2024.08.008Vesicles and mixed micelles in hypothyroid rat bile before and after thyroid hormone treatment: evidence for a vesicle transport system for biliary cholesterol secretion
Journal of Lipid Research · 1994
DOI: 10.1016/s0022-2275(20)40082-3The interplay between thyroid and liver: implications for clinical practice
Journal of Endocrinological Investigation · 2020
DOI: 10.1007/s40618-020-01208-6Thyroid Function and Non-alcoholic Fatty Liver Disease in Children and Adolescent With Obesity: A Systematic Review and Meta-Analysis
Endocrine Practice · 2026
DOI: 10.1016/j.eprac.2026.04.002Conferring liver selectivity to a thyromimetic using a novel nanoparticle increases therapeutic efficacy in a diet-induced obesity animal model
PNAS Nexus · 2023
DOI: 10.1093/pnasnexus/pgad252Thyroid hormone (T3) and TRβ agonist GC-1 inhibit/reverse nonalcoholic fatty liver in rats
The FASEB Journal · 2008
DOI: 10.1096/fj.08-108464Glyoxalase-1 Overexpression Reverses Defective Proangiogenic Function of Diabetic Adipose-Derived Stem Cells in Streptozotocin-Induced Diabetic Mice Model of Critical Limb Ischemia
Stem Cells Translational Medicine · 2017
DOI: 10.5966/sctm.2015-0380Elevation of a Novel Angiogenic Factor, Leucine-Rich-α2-Glycoprotein (LRG1), Is Associated With Arterial Stiffness, Endothelial Dysfunction, and Peripheral Arterial Disease in Patients With Type 2 Diabetes
The Journal of Clinical Endocrinology & Metabolism · 2015
DOI: 10.1210/jc.2014-3855Dipyridamole reverses peripheral ischemia and induces angiogenesis in the Db/Db diabetic mouse hind-limb model by decreasing oxidative stress
Free Radical Biology and Medicine · 2011
DOI: 10.1016/j.freeradbiomed.2010.10.714Early life nicotine exposure alters mRNA and microRNA expressions related to thyroid function and lipid metabolism in liver and BAT of adult wistar rats
Molecular and Cellular Endocrinology · 2021
DOI: 10.1016/j.mce.2020.111141PEGylated substance P augments therapeutic angiogenesis in diabetic critical limb ischemia
Journal of Industrial and Engineering Chemistry · 2019
DOI: 10.1016/j.jiec.2019.05.030High-density lipoprotein-mimicking nanodiscs carrying peptide for enhanced therapeutic angiogenesis in diabetic hindlimb ischemia
Biomaterials · 2018
DOI: 10.1016/j.biomaterials.2018.01.027The influence of hypothyroidism on the transport of phosphate and on the lipid composition in rat-liver mitochondria
Biochimica et Biophysica Acta (BBA) - Biomembranes · 1991
DOI: 10.1016/0005-2736(91)90161-zDeletion of AT2 Receptor Prevents SHP-1–Induced VEGF Inhibition and Improves Blood Flow Reperfusion in Diabetic Ischemic Hindlimb
Arteriosclerosis, Thrombosis, and Vascular Biology · 2017
DOI: 10.1161/atvbaha.117.309977Effects of PEMF on microcirculation and angiogenesis in a model of acute hindlimb ischemia in diabetic rats
Bioelectromagnetics · 2013
DOI: 10.1002/bem.21755Advances in Treating the Ischaemic Diabetic Foot
Current Vascular Pharmacology · 2008
DOI: 10.2174/157016108783331330Vascular endothelial cell growth factor and fibroblast growth factor 2 expression in patients with critical limb ischemia
Journal of Vascular Surgery · 2004
DOI: 10.1016/j.jvs.2003.07.006Therapeutical potential of autologous peripheral blood mononuclear cell transplantation in patients with type 2 diabetic critical limb ischemia
Journal of Diabetes and its Complications · 2012
DOI: 10.1016/j.jdiacomp.2011.11.007High-fat diet pre-conditioning improves microvascular remodelling during regeneration of ischaemic mouse skeletal muscle
Acta Physiologica · 2020
DOI: 10.1111/apha.13449Overt hypothyroidism complicated by complete heart block and severe hyperlipidemia. A case report
Annals of Medicine & Surgery · 2022
DOI: 10.1016/j.amsu.2022.104830Thyroid replacement therapy and its influence on postheparin plasma lipases and apolipoprotein-B metabolism in hypothyroidism
Journal of Clinical Endocrinology & Metabolism · 1993
DOI: 10.1210/jc.76.5.1209Effect of 6 months intense Yoga practice on lipid profile, thyroxine medication and serum TSH level in women suffering from hypothyroidism: A pilot study
Journal of Complementary and Integrative Medicine · 2016
DOI: 10.1515/jcim-2014-0079Prevalence of subclinical hypothyroidism and longitudinal thyroid-stimulating hormone changes in youth with metabolic dysfunction–associated steatotic liver disease: An observational study
Hepatology · 2025
DOI: 10.1097/hep.0000000000001095Effects of l-Triiodothyronine and the Thyromimetic L-94901 on Serum Lipoprotein Levels and Hepatic Low-Density Lipoprotein Receptor, 3-Hydroxy-3-methylglutaryl Coenzyme A Reductase, and Apo A-I Gene Expression
Biochemical Pharmacology · 1998
DOI: 10.1016/s0006-2952(98)00119-1Difference in Serum Endostatin Levels in Diabetic Patients with Critical Limb Ischemia Treated by Autologous Cell Therapy or Percutaneous Transluminal Angioplasty
Cell Transplantation · 2018
DOI: 10.1177/0963689718775628Effect of thyroid hormone on hepatic cholesterol 7α hydroxylase, LDL receptor, HMG-CoA reductase, farnesyl pyrophosphate synthetase and apolipoprotein A-I mRNA levels in hypophysectomized rats
Biochemical and Biophysical Research Communications · 1990
DOI: 10.1016/0006-291x(90)91568-dSelective Agonists of Thyroid Hormone Receptor Beta for the Treatment of NASH
New England Journal of Medicine · 2024
DOI: 10.1056/nejme2314365A Phase 3 Trial of Resmetirom in NASH with Liver Fibrosis
New England Journal of Medicine · 2024
DOI: 10.1056/nejmc2402905The effect of levothyroxine replacement therapy on lipid profile and oxidative stress parameters in patients with subclinical hypothyroid
Archives of Pharmacal Research · 2021
DOI: 10.1007/s12272-013-0227-yA selective decline of postheparin plasma hepatic triglyceride lipase in hypothyroid rats
Metabolism · 1980
DOI: 10.1016/0026-0495(80)90207-3Lipid Metabolism in Pregnancy Women with Hypothyroidism and Potential Influence on Pregnancy Outcome
Journal of Lipids · 2024
DOI: 10.1155/2024/5589492Analysis of haemodynamics and angiogenic response to ischaemia in the obese type 2 diabetic model Spontaneously Diabetic Torii Lepr fa (SDT fatty) rats
Clinical and Experimental Pharmacology and Physiology · 2020
DOI: 10.1111/1440-1681.13239Thyroid Hormone Receptor-α Gene Knockout Mice Are Protected from Diet-Induced Hepatic Insulin Resistance
Endocrinology · 2012
DOI: 10.1210/en.2011-1793Modulation by Thyroid Status of Hepatic Low KmPhosphodiesterase*
Endocrinology · 1982
DOI: 10.1210/endo-110-1-260Novel Receptor for Advanced Glycation End Products-Blocking Antibody to Treat Diabetic Peripheral Artery Disease
Journal of the American Heart Association · 2021
DOI: 10.1161/jaha.120.016696Cardiovascular risk factors cause premature rarefaction of the collateral circulation and greater ischemic tissue injury
Angiogenesis · 2015
DOI: 10.1007/s10456-015-9465-6Decreased Expression of Hepatic Low-Density Lipoprotein Receptor–Related Protein 1 in Hypothyroidism: A Novel Mechanism of Atherogenic Dyslipidemia in Hypothyroidism
Thyroid · 2013
DOI: 10.1089/thy.2012.0457Glypican-1 nanoliposomes for potentiating growth factor activity in therapeutic angiogenesis
Biomaterials · 2016
DOI: 10.1016/j.biomaterials.2016.03.048Therapeutic Outcomes of Transplanting Autologous Granulocyte Colony-stimulating Factor-mobilised Peripheral Mononuclear Cells in Diabetic Patients with Critical Limb Ischaemia
Experimental and Clinical Endocrinology & Diabetes · 2013
DOI: 10.1055/s-0032-1311646Association of the anti-angiogenic factor secreted protein and rich in cysteine (SPARC) with vascular complications among Chinese type 2 diabetic patients in Singapore
Journal of Diabetes and its Complications · 2017
DOI: 10.1016/j.jdiacomp.2016.03.029Thyroidal regulation of substrate kinetics properties of cytochrome oxidase in rat liver mitochondria
Indian Journal of Clinical Biochemistry · 2008
DOI: 10.1007/s12291-008-0061-zLiver X receptor β controls thyroid hormone feedback in the brain and regulates browning of subcutaneous white adipose tissue
Proceedings of the National Academy of Sciences · 2015
DOI: 10.1073/pnas.1519358112Therapeutic Angiogenesis by Autologous Bone Marrow Cell Implantation for Refractory Chronic Peripheral Arterial Disease Using Assessment of Neovascularization by 99mTc-Tetrofosmin (TF) Perfusion Scintigraphy
Cell Transplantation · 2004
DOI: 10.3727/000000004783983837Metabolic Dysfunction–Associated Fatty Liver Disease (MAFLD) and Thyroid Function in Childhood Obesity: A Vicious Circle?
Children · 2024
DOI: 10.3390/children11020244Placental mesenchymal stromal cells as an alternative tool for therapeutic angiogenesis
Cellular and Molecular Life Sciences · 2020
DOI: 10.1007/s00018-019-03268-1TSH-Controlled l -Thyroxine Therapy Reduces Cholesterol Levels and Clinical Symptoms in Subclinical Hypothyroidism: A Double Blind, Placebo-Controlled Trial (Basel Thyroid Study)
The Journal of Clinical Endocrinology & Metabolism · 2001
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