公开文献目录 · 777

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• Low Free Triiodothyronine Is Associated with Advanced Fibrosis in Patients at High Risk for Nonalcoholic Steatohepatitis

  Digestive Diseases and Sciences · 2019

  Paul Manka, Lars Bechmann, Jan Best, Svenja Sydor, Lee C. Claridge, Jason D. Coombes, Ali Canbay, Lars Moeller, Guido Gerken, Heiner Wedemeyer, Wing-Kin Syn

  DOI: 10.1007/s10620-019-05687-3

• Rationale and design of the granulocyte-macrophage colony stimulating factor in peripheral arterial disease (GPAD-3) study

  Contemporary Clinical Trials · 2020

  Anurag Mehta, Kreton Mavromatis, Yi-An Ko, Steven C. Rogers, Devinder S. Dhindsa, Cydney Goodwin, Risha Patel, Mohammad A. Martini, Mahadev Prasad, Ali Mokhtari, Iraj G. Hesaroieh, Stephen C. Frohwein, Michael H. Kutner, Arash Harzand, Bryan J. Wells, Yazan Duwayri, Olamide Alabi, Ravi R. Rajani, Luke P. Brewster, Edmund K. Waller, Arshed A. Quyyumi

  DOI: 10.1016/j.cct.2020.105975

• Co-targeting ASK1 and THRβ synergistically improves steatohepatitis and fibrosis in a MASH animal model

  Biochemical and Biophysical Research Communications · 2024

  Shu Shang, Qin Wan, Faxiu Chen, Jian Hu

  DOI: 10.1016/j.bbrc.2024.149739

• Elevated Monocytes in Patients with Critical Limb Ischemia Diminish After Bypass Surgery

  Journal of Surgical Research · 2011

  Dania Magri, Penny Vasilas, Akihito Muto, Tamara N. Fitzgerald, Tiffany T. Fancher, Aaron J. Feinstein, Toshiya Nishibe, Alan Dardik

  DOI: 10.1016/j.jss.2009.06.014

• Impact of peripheral thyroid hormone balance on liver fat: insights from the NutriAct trial

  European Journal of Endocrinology · 2024

  Miriam Sommer-Ballarini, Thu-Huong Nguyen, Laura Pletsch-Borba, Charlotte Wernicke, Frank Tacke, Tanja Schwerdtle, Denny Pellowski, Jürgen Machann, Joachim Spranger, Eva Katrin Wirth, Knut Mai

  DOI: 10.1093/ejendo/lvae093

• Activation of the hepatic LDL receptor promoter by thyroid hormone

  Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · 2007

  Dayami Lopez, Jose F. Abisambra Socarrás, Mohini Bedi, Gene C. Ness

  DOI: 10.1016/j.bbalip.2007.05.001

• Thyroid-Liver Axis: The Role of Thyroid Dysfunction in the Pathogenesis and Progression of MASLD: A Comprehensive Review

  Liver International · 2026

  Stefania Capuccio, Graziella Privitera, Sabrina Scilletta, Francesca La Rocca, Maurizio Di Marco, Roberto Scicali, Antonino Di Pino, Salvatore Piro, Maurizio Russello

  DOI: 10.1111/liv.70431

• Beneficial effects of Cinnamon on hepatic lipid metabolism are impaired in hypothyroid rats

  Journal of Functional Foods · 2018

  Bruna Pereira Lopes, Thaiane Gadioli Gaique, Luana Lopes Souza, Gabriela Silva Monteiro Paula, George E.G. Kluck, Georgia C. Atella, Carmen Cabanelas Pazos-Moura, Karen Jesus Oliveira

  DOI: 10.1016/j.jff.2018.10.002

• Transplantation of Mesenchymal Cells Improves Peripheral Limb Ischemia in Diabetic Rats

  Molecular Biotechnology · 2014

  Rosalinda Madonna, Stefano Delli Pizzi, Armando Tartaro, Raffaele De Caterina

  DOI: 10.1007/s12033-014-9735-3

• Thyroid function, adipokines and mitokines in metabolic dysfunction-associated steatohepatitis: A multi-centre biopsy-based observational study

  Liver International · 2024

  Matina Kouvari, Laura Valenzuela‐Vallejo, Evangelos Axarloglou, Ornella Verrastro, Georgios Papatheodoridis, Geltrude Mingrone, Jacob George, Christos S. Mantzoros

  DOI: 10.1111/liv.15847

• Association of thyroid function with non-alcoholic fatty liver disease in recent-onset diabetes

  Liver International · 2024

  Nina Saatmann, Martin Schön, Oana‐Patricia Zaharia, Maximilian Huttasch, Klaus Strassburger, Sandra Trenkamp, Yuliya Kupriyanova, Vera Schrauwen‐Hinderling, Sabine Kahl, Volker Burkart, Robert Wagner, Michael Roden, for the GDS Group

  DOI: 10.1111/liv.15723

• Discovery of Salidroside-Derivated Glycoside Analogues as Novel Angiogenesis Agents to Treat Diabetic Hind Limb Ischemia

  Journal of Medicinal Chemistry · 2022

  Caiping Liu, Jingxuan Han, Olivia Marcelina, Dyah Ari Nugrahaningrum, Song Huang, Meijuan Zou, Guixue Wang, Makoto Miyagishi, Yun He, Shourong Wu, Vivi Kasim

  DOI: 10.1021/acs.jmedchem.1c00947

• Vaccarin Regulates Diabetic Chronic Wound Healing through FOXP2/AGGF1 Pathways

  International Journal of Molecular Sciences · 2020

  Yixiao Liu, Jiangnan Sun, Xinyu Ma, Shuangshuang Li, Min Ai, Fei Xu, Liying Qiu

  DOI: 10.3390/ijms21061966

• Endothelial Progenitor Cells (EPCs) Mobilized and Activated by Neurotrophic Factors May Contribute to Pathologic Neovascularization in Diabetic Retinopathy

  The American Journal of Pathology · 2010

  Xialin Liu, Yongjun Li, Yizhi Liu, Yan Luo, Dingding Wang, Brian H. Annex, Pascal J. Goldschmidt-Clermont

  DOI: 10.2353/ajpath.2010.081152

• A multifunctional role of Leucine-rich-alpha 2 glycoprotein 1 in cutaneous wound healing under normal and diabetic conditions

  Diabetes · 2020

  Ada Admin, Chenghao Liu, Melissa Hui Yen Teo, Sharon Li Ting Pek, Wu Xiaoting, Mei Ling Leong, Hui Min Tay, Han Wei Hou, Ruedl Christiane, Stephen E. Moss, John Greenwood, Subramaniam Tavintharan, Wanjin Hong, Xiaomeng Wang

  DOI: 10.2337/figshare.12860753.v1

• Liraglutide Accelerates Ischemia-Induced Angiogenesis in a Murine Diabetic Model

  Journal of the American Heart Association · 2023

  Yu‐xin Zhu, Yi Li, Yu Ma, Xiao Zhang, Xingrong Du, Jiali Gao, Nian Hui Ding, Liqun Wang, Ni Chen, Mao Luo, Jianbo Wu, Rong Li

  DOI: 10.1161/jaha.122.026586

• The Effect of Iatrogenic Hypothyroidism on Lipoprotein Subfractions and Markers of HDL Function in Patients with Differentiated Thyroid Carcinoma

  Life · 2026

  Mónika Katkó, Annamária Gazdag, Anita Szentpéteri, Hajnalka Lőrincz, Erika Galgoczi, Annamária Erdei, Eszter Berta, Miklós Bodor, Endre V. Nagy, Mariann Harangi

  DOI: 10.3390/life16071083

• Transplantation of Human Placenta-Derived Mesenchymal Stem Cells Alleviates Critical Limb Ischemia in Diabetic Nude Rats

  Cell Transplantation · 2017

  Lu Liang, Zongjin Li, Tao Ma, Zhibo Han, Wenjing Du, Jie Geng, Honghong Jia, Meng Zhao, Jimin Wang, Bingjing Zhang, Jie Feng, Lanzhen Zhao, Alain Rupin, Youwei Wang, Zhong Chao Han

  DOI: 10.3727/096368916x692726

• In Mice With Type 2 Diabetes, a Vascular Endothelial Growth Factor (VEGF)-Activating Transcription Factor Modulates VEGF Signaling and Induces Therapeutic Angiogenesis After Hindlimb Ischemia

  Diabetes · 2007

  Yongjun Li, Surovi Hazarika, Donghua Xie, Anne M. Pippen, Christopher D. Kontos, Brian H. Annex

  DOI: 10.2337/db06-0999

• Adiponectin Pretreatment Counteracts the Detrimental Effect of a Diabetic Environment on Endothelial Progenitors

  Diabetes · 2011

  Simon F. Leicht, Theresa M. Schwarz, Patrick C. Hermann, Jochen Seissler, Alexandra Aicher, Christopher Heeschen

  DOI: 10.2337/db10-0240

• Pretreatment of Diabetic Adipose-derived Stem Cells with mitoTEMPO Reverses their Defective Proangiogenic Function in Diabetic Mice with Critical Limb Ischemia

  Cell Transplantation · 2019

  Kun Lian, Qin Wang, Shuai Zhao, Maosen Yang, Genrui Chen, Youhu Chen, Congye Li, Haokao Gao, Chengxiang Li

  DOI: 10.1177/0963689719885076

• Co-delivery of FGF-2 and G-CSF from gelatin-based hydrogels as angiogenic therapy in a murine critical limb ischemic model

  Acta Biomaterialia · 2009

  H LAYMAN, M SACASA, A MURPHY, A MURPHY, S PHAM, F ANDREOPOULOS

  DOI: 10.1016/j.actbio.2008.07.024

• Impact of thyroid disorders on the incidence of non-alcoholic fatty liver disease in Germany

  United European Gastroenterology Journal · 2021

  Christian Labenz, Karel Kostev, Angelo Armandi, Peter R. Galle, Jörn M. Schattenberg

  DOI: 10.1002/ueg2.12124

• Effect of hyperthyroidism and hypothyroidism on lipid and carbohydrate metabolism of the perfused rat liver

  Biochemical Journal · 1981

  M E Laker, P A Mayes

  DOI: 10.1042/bj1960247

• microRNA-29a Regulates ADAM12 Through Direct Interaction With ADAM12 mRNA and Modulates Postischemic Perfusion Recovery

  Journal of the American Heart Association · 2022

  Victor Lamin, Joseph Verry, Olumayowa S. Dokun, Ana Kronemberger, Thomas Wong, Vitor A. Lira, Ayotunde O. Dokun

  DOI: 10.1161/jaha.122.025727

• Circulating Vascular Endothelial Growth Factor (VEGF) Levels in Advanced Stage Cancer Patients Compared to Normal Controls and Diabetes Mellitus Patients with Critical Ischemia

  Drug Target Insights · 2007

  Yoka H. Kusumanto, Coby Meijer, Wendy Dam, Nanno H. Mulder, Geke A.P. Hospers

  DOI: 10.1177/117739280700200005

• Treatment with Intramuscular Vascular Endothelial Growth Factor Gene Compared with Placebo for Patients with Diabetes Mellitus and Critical Limb Ischemia: A Double-Blind Randomized Trial

  Human Gene Therapy · 2006

  Y.H. Kusumanto, V. van Weel, N.H. Mulder, A.J. Smit, J.J.A.M. van den Dungen, J.M.M. Hooymans, W.J. Sluiter, R.A. Tio, P.H.A. Quax, R.O.B. Gans, R.P.F. Dullaart, G.A.P. Hospers

  DOI: 10.1089/hum.2006.17.683

• Aktuelles zur diabetischen Makroangiopathie

  Der Pathologe · 2012

  J. Kunz

  DOI: 10.1007/s00292-011-1554-8

• A direct comparison of endothelial progenitor cell dysfunction in rat metabolic syndrome and diabetes

  Atherosclerosis · 2013

  Michael A. Kuliszewski, Michael R. Ward, James W. Kowalewski, Alexandra H. Smith, Duncan J. Stewart, Michael J. Kutryk, Howard Leong-Poi

  DOI: 10.1016/j.atherosclerosis.2012.09.029

• Incremental effects of diabetes mellitus and chronic kidney disease in medial arterial calcification: Synergistic pathways for peripheral artery disease progression

  Vascular Medicine · 2019

  Prakash Krishnan, Pedro R Moreno, Irene C Turnbull, Meerarani Purushothaman, Urooj Zafar, Arthur Tarricone, Sandeep Singla, Annapoorna Kini, Samin Sharma, Jagat Narula, Juan J Badimon, K-Raman Purushothaman

  DOI: 10.1177/1358863x19842276

• Association of thyroid autoimmunity with nonalcoholic fatty liver disease in euthyroid middle-aged subjects: A population-based study

  Journal of Gastroenterology and Hepatology · 2022

  Hye Jeong Kim, Sang Joon Park, Hyeong Kyu Park, Dong Won Byun, Kyoil Suh, Myung Hi Yoo

  DOI: 10.1111/jgh.15865

• Oxidation of cholesterol by rat liver mitochondria: Effect of thyroidectomy

  Journal of Cellular and Comparative Physiology · 1965

  David Kritchevsky, Shirley A. Tepper

  DOI: 10.1002/jcp.1030660109

• Importance of thyroid-stimulating hormone levels in liver disease

  Journal of Pediatric Endocrinology and Metabolism · 2020

  Hyun Jin Kim

  DOI: 10.1515/jpem-2020-0031

• Low Thyroid Function in Nonalcoholic Fatty Liver Disease Is an Independent Predictor of All-Cause and Cardiovascular Mortality

  American Journal of Gastroenterology · 2020

  Donghee Kim, Luis Miguel Vazquez-Montesino, Jessica A. Escober, Christopher T. Fernandes, George Cholankeril, Rohit Loomba, Stephen A. Harrison, Zobair M. Younossi, Aijaz Ahmed

  DOI: 10.14309/ajg.0000000000000654

• Subclinical Hypothyroidism and Low-Normal Thyroid Function Are Associated With Nonalcoholic Steatohepatitis and Fibrosis

  Clinical Gastroenterology and Hepatology · 2018

  Donghee Kim, Won Kim, Sae Kyung Joo, Jeong Mo Bae, Jung Ho Kim, Aijaz Ahmed

  DOI: 10.1016/j.cgh.2017.08.014

• Diabetic Mesenchymal Stem Cells Are Ineffective for Improving Limb Ischemia Due to Their Impaired Angiogenic Capability

  Cell Transplantation · 2015

  Hyongbum Kim, Ji Woong Han, Ji Yoon Lee, Yong Jin Choi, Young-Doug Sohn, Myungjae Song, Young-Sup Yoon

  DOI: 10.3727/096368914x682792

• Pan-PPAR Agonist, Bezafibrate, Restores Angiogenesis in Hindlimb Ischemia in Normal and Diabetic Rats

  International Journal of Peptides · 2012

  M. Khazaei, E. Salehi, B. Rashidi

  DOI: 10.1155/2012/637212

• Role of peroxisome proliferator-activated receptor β agonist on angiogenesis in hindlimb ischemic diabetic rats

  Journal of Diabetes and its Complications · 2012

  M. Khazaei, E. Salehi, B. Rashidi, S.H. Javanmard, A.R. Fallahzadeh

  DOI: 10.1016/j.jdiacomp.2012.02.005

• Gene Therapeutic Strategies for Peripheral Artery Disease and New Opportunities Provided by Adeno-Associated Virus Vectors

  Arteriosclerosis, Thrombosis, and Vascular Biology · 2023

  Levon M. Khachigian, Ramon L. Varcoe, Tuisku Suoranta, Nihay Laham-Karam, Seppo Ylä-Herttuala

  DOI: 10.1161/atvbaha.122.318902

• Role of the Bile Acid Transporter SLC10A1 in Liver Targeting of the Lipid-Lowering Thyroid Hormone Analog Eprotirome

  Endocrinology · 2017

  Simone Kersseboom, Anja L. M van Gucht, Alies van Mullem, Giulia Brigante, Stefania Farina, Bo Carlsson, Joanne M Donkers, Stan F. J van de Graaf, Robin P Peeters, Theo J Visser

  DOI: 10.1210/en.2017-00433

• Discovery of 2-[3,5-Dichloro-4-(5-isopropyl-6-oxo-1,6-dihydropyridazin-3-yloxy)phenyl]-3,5-dioxo-2,3,4,5-tetrahydro[1,2,4]triazine-6-carbonitrile (MGL-3196), a Highly Selective Thyroid Hormone Receptor β Agonist in Clinical Trials for the Treatment of Dyslipidemia

  Journal of Medicinal Chemistry · 2014

  Martha J. Kelly, Sherrie Pietranico-Cole, J. Douglas Larigan, Nancy-Ellen Haynes, Charles H. Reynolds, Nathan Scott, John Vermeulen, Mark Dvorozniak, Karin Conde-Knape, Kuo-Sen Huang, Sung-Sau So, Kshitij Thakkar, Yimin Qian, Bruce Banner, Frank Mennona, Sara Danzi, Irwin Klein, Rebecca Taub, Jefferson Tilley

  DOI: 10.1021/jm4019299

• Peripheral Arterial Disease in Diabetes: Is There a Role for Genetics?

  Current Diabetes Reports · 2011

  Arabindra B. Katwal, Ayotunde O. Dokun

  DOI: 10.1007/s11892-011-0188-9

• Hydrolase activities in the rat aorta. V. Comparison to activities in liver and kidney after thyroidectomy and relation to dynamic clearance of circulating low density lipoproteins

  Circulation Research · 1981

  D Katz-Feigenbaum, L Braun, H Wolinsky

  DOI: 10.1161/01.res.49.3.733

• Ghrelin Promotes Functional Angiogenesis in a Mouse Model of Critical Limb Ischemia Through Activation of Proangiogenic MicroRNAs

  Endocrinology · 2016

  Rajesh Katare, Shruti Rawal, Pujika Emani Munasinghe, Hirotsugu Tsuchimochi, Tadakatsu Inagaki, Yutaka Fujii, Parul Dixit, Keiji Umetani, Kenji Kangawa, Mikiyasu Shirai, Daryl O. Schwenke

  DOI: 10.1210/en.2015-1799

• Leptin, cardiovascular diseases and type 2 diabetes mellitus

  Acta Pharmacologica Sinica · 2018

  Niki Katsiki, Dimitri P Mikhailidis, Maciej Banach

  DOI: 10.1038/aps.2018.40

• Clinical-Grade Human Neural Stem Cells Promote Reparative Neovascularization in Mouse Models of Hindlimb Ischemia

  Arteriosclerosis, Thrombosis, and Vascular Biology · 2014

  Rajesh Katare, Paul Stroemer, Caroline Hicks, Lara Stevanato, Sara Patel, Randolph Corteling, Erik Miljan, Indira Vishnubhatla, John Sinden, Paolo Madeddu

  DOI: 10.1161/atvbaha.113.302592

• Perivascular Delivery of Encapsulated Mesenchymal Stem Cells Improves Postischemic Angiogenesis Via Paracrine Activation of VEGF-A

  Arteriosclerosis, Thrombosis, and Vascular Biology · 2013

  Rajesh Katare, Federica Riu, Jonathan Rowlinson, Andrew Lewis, Rachel Holden, Marco Meloni, Carlotta Reni, Christine Wallrapp, Costanza Emanueli, Paolo Madeddu

  DOI: 10.1161/atvbaha.113.301217

• Activation of thyroid hormone receptor-β improved disease activity and metabolism independent of body weight in a mouse model of non-alcoholic steatohepatitis and fibrosis

  British Journal of Pharmacology · 2021

  Aimo Kannt, Paulus Wohlfart, Andreas Nygaard Madsen, Sanne Skovgård Veidal, Michael Feigh, Dieter Schmoll

  DOI: 10.1111/bph.15427

• Thyroidectomy stimulates glucagon-like peptide-1 secretion and attenuates hepatic steatosis in high-fat fed rats

  Biochemical and Biophysical Research Communications · 2017

  Jong Yeon Kang, Mikyung Kim, Yuna Kang, Wonmok Lee, Tae Kyung Ha, Ji Hae Seo, Young Gil Son, Eunyoung Ha

  DOI: 10.1016/j.bbrc.2017.08.154

• Exendin-4 protects hindlimb ischemic injury by inducing angiogenesis

  Biochemical and Biophysical Research Communications · 2015

  Hye-Min Kang, Inkyung Sohn, Junyang Jung, Joo-Won Jeong, Chan Park

  DOI: 10.1016/j.bbrc.2015.08.080

• Thyroid dysfunction and hepatic steatosis in overweight children and adolescents

  Pediatric Obesity · 2017

  T. E.‐M. Kaltenbach, T. Graeter, S. Oeztuerk, D. Holzner, W. Kratzer, M. Wabitsch, C. Denzer

  DOI: 10.1111/ijpo.12110

• A hypoxic inducible factor-1α hybrid enhances collateral development and reduces vascular leakage in diabetic rats

  The Journal of Gene Medicine · 2009

  Hidetoshi Kajiwara, Zhengyu Luo, Adam J. Belanger, Akihiro Urabe, Karen A. Vincent, Geoffrey Y. Akita, Seng H. Cheng, Seibu Mochizuki, Richard J. Gregory, Canwen Jiang

  DOI: 10.1002/jgm.1318

• Decreased mobilization of endothelial progenitor cells contributes to impaired neovascularization in diabetes

  Clinical and Experimental Pharmacology and Physiology · 2009

  Lina Kang, Qin Chen, Lian Wang, Ling Gao, Kui Meng, Junhao Chen, Albert Ferro, Biao Xu

  DOI: 10.1111/j.1440-1681.2009.05219.x

• The real face of endothelial progenitor cells – Circulating angiogenic cells as endothelial prognostic marker?

  Pharmacological Reports · 2015

  Neli Kachamakova-Trojanowska, Karolina Bukowska-Strakova, Monika Zukowska, Jozef Dulak, Alicja Jozkowicz

  DOI: 10.1016/j.pharep.2015.05.017

• Thyroid Function and Serum Hepatic Enzyme Activity in Dogs after Phenobarbital Administration

  Journal of Veterinary Internal Medicine · 2000

  Tracy L Gieger, Giselle Hosgood, Joseph Taboada, Karen J Wolfsheimer, Peter B Mueller

  DOI: 10.1111/j.1939-1676.2000.tb01167.x

• Peripheral arterial disease in diabetes—a review

  Diabetic Medicine · 2010

  E. B. Jude, I. Eleftheriadou, N. Tentolouris

  DOI: 10.1111/j.1464-5491.2009.02866.x

• Serum levels of lead are associated with venous thromboembolism: a retrospective study based on the NHANES database (1999 to 2018)

  Journal of Thoracic Disease · 2023

  Min Xiao, Dan Li, Xiaoqian Wang, Jing Zhang, Xiaoping Wang, Jiao Gao

  DOI: 10.21037/jtd-23-1071

• Inverse Association Between Serum Free Thyroxine Levels and Hepatic Steatosis: Results from the Study of Health in Pomerania

  Thyroid · 2012

  Till Ittermann, Robin Haring, Henri Wallaschofski, Sebastian E. Baumeister, Matthias Nauck, Marcus Dörr, Markus M. Lerch, Henriette E. Meyer zu Schwabedissen, Dieter Rosskopf, Henry Völzke

  DOI: 10.1089/thy.2011.0279

• Intramuscular injection of sotagliflozin promotes neovascularization in diabetic mice through enhancing skeletal muscle cells paracrine function

  Acta Pharmacologica Sinica · 2022

  Lai-liu Luo, Jing-xuan Han, Shou-rong Wu, Vivi Kasim

  DOI: 10.1038/s41401-022-00889-4

• Resmetirom: The First Disease-Specific Treatment for MASH

  International Journal of Endocrinology · 2025

  Ali Mohamed Mousa, Mervat Mahmoud, Ghaida Mubarak AlShuraiaan

  DOI: 10.1155/ije/6430023

• CS27109, A Selective Thyroid Hormone Receptor-β Agonist Alleviates Metabolic-Associated Fatty Liver Disease in Murine Models

  International Journal of Endocrinology · 2023

  Shengjian Huang, Zhou Deng, Wei Wang, Guoqiang Liao, Yiru Zhao, Hua Zhong, Qian Zhang, Jing Liu, Xuhua Mao, Beizhong Chen, Desi Pan, You Zhou

  DOI: 10.1155/2023/4950597

• Peripheral T3 signaling is the target of pesticides in zebrafish larvae and adult liver

  Journal of Endocrinology · 2020

  Marco Colella, Valeria Nittoli, Alfonsina Porciello, Immacolata Porreca, Carla Reale, Filomena Russo, Nicola Antonino Russo, Luca Roberto, Francesco Albano, Mario De Felice, Massimo Mallardo, Concetta Ambrosino

  DOI: 10.1530/joe-20-0134

• JNK1 in SF1 neurons regulates the central action of thyroid hormones on hepatic lipid metabolism

  Molecular Metabolism · 2025

  Iara Fernández-González, Oscar Freire-Agulleiro, Vitor Ferreira, María Silveira-Loureiro, Eva Rial-Pensado, Pablo Garrido-Gil, Gloria Martínez, Patricia Rada, José L. Labandeira-García, Jens Mittag, Ismael González-García, Carlos Diéguez, Rubén Nogueiras, Ángela M. Valverde, Roger J. Davis, Guadalupe Sabio, Olga Barca-Mayo, Miguel López

  DOI: 10.1016/j.molmet.2025.102170

• Therapeutic Effects of Hydroalcoholic Extract of Black Seed (Nigella sativa L.) and Honey on Biochemical Parameters, Thyroid Hormones, and Liver Tissue in Streptozotocin-Induced Diabetic Male Rats

  Journal of Medicinal Plants and By-products · 2025

  Zainab Rezaei, Mokhtar Mokhtari, Mehrdad Shariati

  DOI: 10.22034/jmpb.2024.367237.1777

• Design and Evaluation of Conformationally Locked Indole-Carboxylic Acids as Selective THRβ Agonists against MASH

  Journal of Medicinal Chemistry · 2026

  Bo Wang, Yanhao Dong, Hanxiao Zhu, Xingjun Sun, Yongcheng Guo, Zhanyan Liu, Yeying Zeng, Junlu Chu, Ruijie Nie, Zhimin Zhang, Zixuan Ma, Liwei Shao, Kai Tang, Ying Zhi

  DOI: 10.1021/acs.jmedchem.6c01478

• Discovery of Highly Potent and Selective Thyroid Hormone Receptor β Agonists for the Treatment of Nonalcoholic Steatohepatitis

  Journal of Medicinal Chemistry · 2023

  Liuyu Hu, Yipei Gu, Ju Liang, Mengmeng Ning, Junli Yang, Yi Zhang, Hui Qu, Yaxi Yang, Ying Leng, Bing Zhou

  DOI: 10.1021/acs.jmedchem.2c01669

• Low thyroid function is associated with metabolic dysfunction-associated steatotic liver disease

  JGH Open · 2024

  Shuo Wang, Ding Xia, Hong Fan, Zhenqiu Liu, Ruilin Chen, Chen Suo, Tiejun Zhang

  DOI: 10.1002/jgh3.13038

• Discovery and Preclinical Profile of ALG-055009, a Potent and Selective Thyroid Hormone Receptor Beta (THR-β) Agonist for the Treatment of MASH

  Journal of Medicinal Chemistry · 2024

  Koen Vandyck, David C. McGowan, Xuan G. Luong, Sarah K. Stevens, Andreas Jekle, Kusum Gupta, Dinah L. Misner, Sushmita Chanda, Vladimir Serebryany, Michael Welch, Haiyang Hu, Zhidan Lv, Caroline Williams, Klaus Maskos, Alfred Lammens, Antitsa D. Stoycheva, Tse-I Lin, Lawrence M. Blatt, Leonid N. Beigelman, Julian A. Symons, Pierre Raboisson, Jerome Deval

  DOI: 10.1021/acs.jmedchem.4c01029

• Nonalcoholic Fatty Liver Disease Is Not Associated with Thyroid Hormone Levels and Hypothyroidism: A Systematic Review and Meta-Analysis

  European Thyroid Journal · 2017

  Veeravich Jaruvongvanich, Anawin Sanguankeo, Sikarin Upala

  DOI: 10.1159/000454920

• Thyromimetics and MASLD: Unveiling the Novel Molecules Beyond Resmetirom

  Journal of Gastroenterology and Hepatology · 2025

  Devaraj Ezhilarasan

  DOI: 10.1111/jgh.16874

• Potentially active compounds that improve PAD through angiogenesis: A review

  Biomedicine & Pharmacotherapy · 2023

  Zi-bo Liu, Xin-yun Fan, Chen-wei Wang, Xun Ye, Chun-jie Wu

  DOI: 10.1016/j.biopha.2023.115634

• Endothelium-targeted delivery of PPARδ by adeno-associated virus serotype 1 ameliorates vascular injury induced by hindlimb ischemia in obese mice

  Biomedicine & Pharmacotherapy · 2022

  Yalan Wu, Xiao Lin, Huiling Hong, Yee Lok Fung, Xiaoyun Cao, Joyce Ka Yu Tse, Tsz Ho Li, Ting Fung Chan, Xiao Yu Tian

  DOI: 10.1016/j.biopha.2022.113172

• Muscle Derived Stem Cells Stimulate Muscle Myofiber Repair and Counteract Fat Infiltration in a Diabetic Mouse Model of Critical Limb Ischemia

  Journal of Stem Cell Research & Therapy · 2016

  Tsao J, Kovanecz I, Awadalla N

  DOI: 10.4172/2157-7633.1000370

• Insights into the results of Resmetirom trials: Can a thyroid hormone receptor agonist be the holy grail of MASH therapy?

  Pharmacology & Therapeutics · 2025

  Konstantinos Arvanitakis, Theocharis Koufakis, Evangelos Cholongitas, Sven Francque, Georgios Germanidis

  DOI: 10.1016/j.pharmthera.2025.108811

• Raman spectroscopic characterization of liver steatosis and fibrosis in a 2D and 3D in vitro thyroxine-treated hypothyroid cellular model

  Molecular and Cellular Endocrinology · 2026

  S. Maurotti, B. Scopacasa, F. Scionti, R. Pujia, M. Frosina, A. Mirarchi, N. Geirola, R. Mare, T. Montalcini, P. Candeloro, L. Tirinato, A. Pujia

  DOI: 10.1016/j.mce.2025.112679

• Role of serotonin in angiogenesis: Induction of angiogenesis by sarpogrelate via endothelial 5-HT1B/Akt/eNOS pathway in diabetic mice

  Atherosclerosis · 2012

  Masaaki Iwabayashi, Yoshiaki Taniyama, Fumihiro Sanada, Junya Azuma, Kazuma Iekushi, Hiroshi Kusunoki, Amarnath Chatterjee, Keita Okayama, Hiromi Rakugi, Ryuichi Morishita

  DOI: 10.1016/j.atherosclerosis.2011.10.042

• Incidences of hypothyroidism and autoimmune thyroiditis are increased in patients with nonalcoholic fatty liver disease

  European Journal of Gastroenterology & Hepatology · 2021

  Sven H. Loosen, Münevver Demir, Karel Kostev, Tom Luedde, Christoph Roderburg

  DOI: 10.1097/meg.0000000000002136

• Exercise-Induced Hepatic Mitochondrial Reprogramming Across Muscle–Gut–Thyroid Axes in MASLD/MASH

  International Journal of Molecular Sciences · 2026

  Jonas M. McCaffrey, Jamal A. Ibdah

  DOI: 10.3390/ijms27146112

• Impact of thyroid dysfunction and diabetes on fibrosis and steatosis stages in metabolic dysfunction associated fatty liver disease

  Scientific Reports · 2025

  Mohamed W. Saleh, Maysa I. Farghly, Eman Elsebaie, Nessren Mohamed, Eman El-Mankhly

  DOI: 10.1038/s41598-025-28232-x

• Hepatic Energy Metabolism under the Local Control of the Thyroid Hormone System

  International Journal of Molecular Sciences · 2023

  Joshua Seifert, Yingfu Chen, Wenzel Schöning, Knut Mai, Frank Tacke, Joachim Spranger, Josef Köhrle, Eva Katrin Wirth

  DOI: 10.3390/ijms24054861

• Effect of Liraglutide on Serum TSH Levels in Patients with NAFLD and its Underlying Mechanisms

  International Journal of Clinical Practice · 2022

  JiaoJiao Ye, Jing Xu, WenJie Wen, Bin Huang

  DOI: 10.1155/2022/1786559

• MicroRNA-135a-3p regulates angiogenesis and tissue repair by targeting p38 signaling in endothelial cells

  The FASEB Journal · 2019

  Basak Icli, Winona Wu, Denizhan Ozdemir, Hao Li, Stefan Haemmig, Xin Liu, Giorgio Giatsidis, Henry S. Cheng, Seyma Nazli Avci, Mervé Kurt, Nathan Lee, Raphael Boesche Guimarães, André Manica, Júlio Flávio Meirelles Marchini, S. E. Rynning, Ivar Risnes, Ivana Hollan, Kevin Croce, Dennis P. Orgill, Mark W. Feinberg

  DOI: 10.1096/fj.201802063rr

• MiR-4674 regulates angiogenesis in tissue injury by targeting p38K signaling in endothelial cells

  American Journal of Physiology-Cell Physiology · 2020

  Basak Icli, Hao Li, Daniel Pérez-Cremades, Winona Wu, Denizhan Ozdemir, Stefan Haemmig, Raphael Boesch Guimaraes, Andre Manica, Julio F. Marchini, Dennis P. Orgill, Mark W. Feinberg

  DOI: 10.1152/ajpcell.00542.2019

• Hypothyroidism, lipids, and lipidomics

  Endocrine · 2023

  Jacqueline Jonklaas

  DOI: 10.1007/s12020-023-03420-9

• MicroRNA-615-5p Regulates Angiogenesis and Tissue Repair by Targeting AKT/eNOS (Protein Kinase B/Endothelial Nitric Oxide Synthase) Signaling in Endothelial Cells

  Arteriosclerosis, Thrombosis, and Vascular Biology · 2019

  Basak Icli, Winona Wu, Denizhan Ozdemir, Hao Li, Henry S. Cheng, Stefan Haemmig, Xin Liu, Giorgio Giatsidis, Seyma Nazli Avci, Nathan Lee, Raphael Boesch Guimaraes, Andre Manica, Julio F. Marchini, Stein Erik Rynning, Ivar Risnes, Ivana Hollan, Kevin Croce, Xianbin Yang, Dennis P. Orgill, Mark W. Feinberg

  DOI: 10.1161/atvbaha.119.312726

• Niacin improves ischemia-induced neovascularization in diabetic mice by enhancement of endothelial progenitor cell functions independent of changes in plasma lipids

  Angiogenesis · 2012

  Po-Hsun Huang, Chih-Pei Lin, Chao-Hung Wang, Chia-Hung Chiang, Hsiao-Ya Tsai, Jia-Shiong Chen, Feng-Yen Lin, Hsin-Bang Leu, Tao-Cheng Wu, Jaw-Wen Chen, Shing-Jong Lin

  DOI: 10.1007/s10456-012-9267-z

• Moderate intake of red wine improves ischemia-induced neovascularization in diabetic mice—Roles of endothelial progenitor cells and nitric oxide

  Atherosclerosis · 2010

  Po-Hsun Huang, Hsiao-Ya Tsai, Chao-Hung Wang, Yung-Hsiang Chen, Jia-Shiong Chen, Feng-Yen Lin, Chih-Pei Lin, Tao-Cheng Wu, Masataka Sata, Jaw-Wen Chen, Shing-Jong Lin

  DOI: 10.1016/j.atherosclerosis.2010.06.034

• Pioglitazone ameliorates endothelial dysfunction and restores ischemia-induced angiogenesis in diabetic mice

  Biomedicine & Pharmacotherapy · 2008

  Po-Hsun Huang, Masataka Sata, Hiroaki Nishimatsu, Makoto Sumi, Yasunobu Hirata, Ryozo Nagai

  DOI: 10.1016/j.biopha.2007.06.014

• Simvastatin pretreatment enhances ischemia-induced neovascularization and blood flow recovery in streptozotocin-treated mice

  Journal of Vascular Surgery · 2016

  Po-Hsun Huang, Jian-You Chen, Chi-Yu Chen, Jaw-Wen Chen, Shing-Jong Lin, Chun-Che Shih

  DOI: 10.1016/j.jvs.2014.11.088

• Statin Therapy Reduces Future Risk of Lower-Limb Amputation in Patients With Diabetes and Peripheral Artery Disease

  The Journal of Clinical Endocrinology & Metabolism · 2017

  Chien-Yi Hsu, Yung-Tai Chen, Yu-Wen Su, Chun-Chin Chang, Po-Hsun Huang, Shing-Jong Lin

  DOI: 10.1210/jc.2016-3717

• Randomised comparison of G-CSF-mobilized peripheral blood mononuclear cells versus bone marrow-mononuclear cells for the treatment of patients with lower limb arteriosclerosis obliterans

  Thrombosis and Haemostasis · 2007

  Ping Ping Huang, Xiao Feng Yang, Shan Zhu Li, Jin Chao Wen, Yan Zhang, Zhong Chao Han

  DOI: 10.1160/th07-02-0137

• Association between Thyroid Function and Nonalcoholic Fatty Liver Disease in Euthyroid Type 2 Diabetes Patients

  Journal of Diabetes Research · 2020

  Bin Huang, Shengju Yang, Shandong Ye

  DOI: 10.1155/2020/6538208

• Autologous Transplantation of Granulocyte Colony–Stimulating Factor–Mobilized Peripheral Blood Mononuclear Cells Improves Critical Limb Ischemia in Diabetes

  Diabetes Care · 2006

  Bin Zhou, Pingping Huang, Zhong Chao Han

  DOI: 10.2337/diacare.29.02.06.dc05-1991

• Effects of external counter-pulsation on endothelial function assessed by peripheral artery tonometry, levels of glycaemia and metabolic markers in individuals with type 2 diabetes mellitus

  Diabetes & Metabolic Syndrome: Clinical Research & Reviews · 2020

  Caroline Wei Shan Hoong, Maudrene Luor Shyuan Tan, Shih Ling Kao, Eric Yin Hao Khoo

  DOI: 10.1016/j.dsx.2020.11.003

• Diabetes Mellitus and Ischemic Diseases: Molecular Mechanisms of Vascular Repair Dysfunction

  Arteriosclerosis, Thrombosis, and Vascular Biology · 2014

  Kiave Yune Howangyin, Jean-Sébastien Silvestre

  DOI: 10.1161/atvbaha.114.303090

• Regulation of VEGF in Diabetic Patients with Critical Limb Ischemia

  Annals of Vascular Surgery · 2001

  Irit Hochberg, Aaron Hoffman, Andrew P. Levy

  DOI: 10.1007/s100160010089

• HIF-Prolyl Hydroxylase 2 Inhibition Enhances the Efficiency of Mesenchymal Stem Cell-Based Therapies for the Treatment of Critical Limb Ischemia

  Stem Cells · 2014

  Kiave-Yune HoWangYin, Céline Loinard, Wineke Bakker, Coralie L. Guérin, José Vilar, Clément D'Audigier, Laetitia Mauge, Patrick Bruneval, Joseph Emmerich, Bernard I. Lévy, Jacques Pouysségur, David M. Smadja, Jean-Sébastien Silvestre

  DOI: 10.1002/stem.1540

• Combined therapy for critical limb ischaemia: Biomimetic PLGA microcarriers potentiates the pro-angiogenic effect of adipose tissue stromal vascular fraction cells

  Journal of Tissue Engineering and Regenerative Medicine · 2018

  Laurence Hoareau, Florian Fouchet, Cynthia Planesse, Sophie Mirbeau, Laurence Sindji, Emmanuel Delay, Régis Roche, Claudia N. Montero-Menei, Franck Festy

  DOI: 10.1002/term.2667

• Plasma Lipoproteins and Regulation of Hepatic Metabolism of Fatty Acids in Altered Thyroid States*

  Endocrine Reviews · 1985

  MURRAY HEIMBERG, JOSEPH O. OLUBADEWO, HENRY G. WILCOX

  DOI: 10.1210/edrv-6-4-590

• Reversal of endothelial progenitor cell dysfunction in patients with type 2 diabetes using a conditioned medium of human embryonic stem cell-derived endothelial cells

  Diabetes/Metabolism Research and Reviews · 2012

  Jenny C. Y. Ho, Wing‐Hon Lai, Ming‐Fang Li, Ka‐Wing Au, Mei‐Chu Yip, Navy L. Y. Wong, Ethel S. K. Ng, Francis F. Y. Lam, Chung‐Wah Siu, Hung‐Fat Tse

  DOI: 10.1002/dmrr.2304